Open Position: Scientist – Computational Drug Design

Start Date: February 2023

What we do:
Early Charm creates, owns, and operates businesses that convert science into revenue.

We are the management team, the operators, and the entrepreneurs. We do not write checks and just pop in for board meetings. We show up to our labs, our production facilities, and our offices every day to do all the heavy lifting in our portfolio companies.

Our scientists and engineers work across our entire portfolio, never just one venture. This brings extraordinary expertise to the earliest stages of product development. The lack of silos fosters creativity and attracts the most collaborative people.

Similarly, our sales & marketing team works across our portfolio enabling us to have the voice of customers heard early and often as we consider product development. Add in our experts in law, intellectual property, accounting, finance, licensing, purchasing and more to get the complete team to build our businesses.

What you will do:
You will work with our ventures in the computer aided drug design space (CADD) to screen and model different drug like compounds and molecules against various biological macromolecules (DNA, RNA, proteins).

You will perform protein preparation, virtual screening, pharmacophore modeling, and molecular dynamics simulations. Experience with drug design pipelines, medicinal chemistry, and structural biology knowledge is preferred. Strong presentation and communication skills are required as you will be engaging with customers and non-science professionals to meet milestones and deadlines.

You will draw from your strong technical background and organizational skills on a daily basis while working with moderate direction alongside colleagues to meet project and research timelines.

You will engage with the Technical Sales lead and Chief Science Officer in addition to other technical leads on project status. The position is on-site and full time Monday- Friday work schedule.

What you need to be successful:

  • Experience in Chemistry, Computational or Physics-based sciences
  • Technical aptitude or experience with molecular modeling which includes but is not limited to: protein modeling, molecular dynamics, high throughput virtual screening, pharmacophore modeling, and scientific programming
  • Experience with Shell scripting and Python is required. Familiarity with C/C ++, Fortran, Javascript, and PHP is preferred
  • A creative thinker and an entrepreneurial mindset
  • Interest in speaking with highly technical customers and end users
  • Scientific presentation skill and data reduction for scientist and non-science professionals
  • A willingness to learn about and engage in the business of science

What we will do for you:
Career development is our top priority for you. While we love the idea of people joining Early Charm forever, we are realistic to understand that we may be a stepping stone to other opportunities or a way for you to explore career options. Regardless of your reasons for joining us, our commitment is to help you while you are helping us.

Where you will work:
We are at the center of the entrepreneurial renaissance of Baltimore, giving you the opportunity to interact with some of the nation’s most exciting technology companies. Located at 1100 Wicomico Street, our labs, production space and offices are intermingled with firms doing engineering design, software development, specialty textiles, robotics, and so much more. There is even a brewery.

Diversity, Equity and Inclusion is Our Business:
Creativity is the soul of Early Charm. We expand creativity by actively seeking out and embracing diversity in all its forms. Diversity of thought, of experience, of culture, of race, of expression and ultimately of the individual is, therefore, our soul.

Action and cooperation drive our success at Early Charm. We foster action through equity. Equity means we treat everyone with respect, empower everyone to make decisions, help everyone to advance their career and compensate everyone fairly. We encourage cooperation by being inclusive. Inclusive means celebrating each other’s differences, listening to each other’s views, and empowering each other to be individuals through our own actions. Equity and inclusion, therefore, is our success.


  • Name your own holidays
  • Paid vacation and sick leave
  • Medical, Life and Dental Insurance
  • 401K with matching

How to Join Us:
Please send your resume and cover letter to Olumide Kayode at