Project Description

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Medical device company developing first therapeutic bandage

Overview

The client developed a novel bandage at laboratory scale demonstrating high efficacy intreating skin tumors in animal studies.

Challenge

The project required a high loading of ceramic nanoparticles be incorporated directly into the nanofibers at the time of electrospinning, and the manufacturing process needed to be translated from small lab prototype to a scalable continuous process

Solution

Dipole Materials developed multiple solutions to produce this product including:

  • A newlarge batch synthesis of the ceramic nanoparticle material
  • A needless electrospinning process capable of incorporating up to 50 wt%nanoparticles into thenanofiber
  • A novel packaging system to eliminate nanoparticle loss during subsequentprocessing and application of the bandage

Outcome

  • A bandage with equivalent efficacy to lab prototypes
  • A scalable manufacturing process
  • Process and performance datasufficient for FDA 501k filing

Project Details

CLIENT

Early phase medical device company developing first therapeutic bandage

PROJECT TYPE

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